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[目的]调查分析老年患者医院内真菌感染的高危因素,为控制老年患者医院内真菌感染提供依据。[方法]采用回顾性调查,对2002~2004年住院病例中﹥60岁老年真菌感染病例进行统计分析。[结果]3年间老年患者医院真菌感染117例,感染构成比由2002年的10.16%上升到2004年的16.94%,感染率有逐年上升的趋势,经χ2检验差异有统计学意义(χ2=5.35,P﹤0.05);老年患者医院真菌感染与基础疾病、长期使用广谱抗生素、各种侵入性诊疗技术、年龄老龄化、化疗等诱因密切相关;老年患者医院真菌感染部位以呼吸道最高,占50.42%;引起医院感染的真菌有7个种,其中以白色假丝酵母菌为主,占65.81%,热带假丝酵母菌次之,占23.08%。[结论]对老年患者应积极治疗原发疾病,合理使用抗生素,改善某些医护行为,及时了解医院内真菌感染发生情况,积极采取治疗和预防措施至关重要。
[Objective] To investigate and analyze the risk factors of fungal infection in elderly patients in hospitals, and provide the basis for controlling the fungal infections in elderly patients. [Methods] A retrospective survey was conducted to analyze the prevalence of fungal infections in elderly patients> 60 years old in inpatients from 2002 to 2004. [Results] 117 cases of fungal infection were found in elderly patients in the elderly in three years. The infection ratio increased from 10.16% in 2002 to 16.94% in 2004, and the infection rate increased year by year. The difference was statistically significant (χ2 = 5.35 , P <0.05). Fungal infection in elderly patients was closely related to underlying diseases, long-term use of broad-spectrum antibiotics, various invasive diagnostic techniques, age-related aging and chemotherapy. Elderly patients had the highest respiratory tract infection in the hospital, accounting for 50.42 %. There were 7 kinds of fungi which caused nosocomial infection, of which Candida albicans was the main type, accounting for 65.81%, followed by Candida tropicalis, accounting for 23.08%. [Conclusion] It is very important for elderly patients to actively treat primary diseases, use antibiotics rationally, improve some health care behaviors, understand the occurrence of fungal infections in hospitals in time, and take active treatment and preventive measures.