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微小RNA(miRNAs)是短的大约19～22个核苷酸长的非编码RNA,它具有调节多种细胞的作用。研究发现miRNA存在于人类血液中,血液中的miRNA可能成为诊断疾病的新的生物学标志物。急性心肌梗死是世界上发病率及死亡率极高的疾病,早期正确的诊断可以确保立即开始再灌注治疗,从而减少死亡率。对照急性心肌梗死患者和健康志愿者血浆中miRNA水平,可发现miRNA在心肌梗死患者中组明显升高。
MicroRNAs (miRNAs) are short, approximately 19 to 22 nucleotides long non-coding RNAs that have the ability to regulate a wide variety of cells. The study found that miRNA is present in human blood, and miRNAs in the blood can become new biomarkers for diagnosing disease. Acute myocardial infarction is a disease with a high morbidity and mortality rate in the world. An early and correct diagnosis can ensure immediate reperfusion therapy to reduce mortality. Comparison of miRNA levels in the plasma of patients with acute myocardial infarction and healthy volunteers revealed that miRNAs were significantly elevated in patients with myocardial infarction.