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目的探讨Ⅱ期原发性胃淋巴瘤(PGL)最佳的治疗方案。方法回顾性分析2001年1月-2008年12月在我院诊治的65例临床诊断为Ⅱ期PGL病例资料,比较不同治疗方案的治疗效果。结果所有病例总生存率为75.38%;各组生存率比较手术联合化疗组(81.48%)优于单纯化疗组(71.43%)和单纯手术组(70.59%)(P<0.05)。所有病例平均生存时间为49.54个月;各组平均生存时间比较手术联合化疗组(74.34个月)优于单纯化疗组(69.07个月)和单纯手术组(64.09个月)(P<0.05)。结论手术联合化疗治疗原发性胃淋巴瘤生存率和生存时间优于其他治疗方法。
Objective To investigate the best treatment for stage Ⅱ primary gastric lymphoma (PGL). Methods The clinical data of 65 cases diagnosed as stage Ⅱ PGL from January 2001 to December 2008 in our hospital were retrospectively analyzed. The therapeutic effects of different treatment regimens were compared. Results The overall survival rate of all patients was 75.38%. Survival rate of each group was significantly higher than that of chemotherapy alone group (71.43% vs 70.59%, P <0.05). The average survival time of all cases was 49.54 months. The average survival time of each group was significantly higher than that of chemotherapy alone group (74.34 months) and chemotherapy alone group (69.07 months) and surgery alone group (64.09 months) (P <0.05). Conclusion Surgical combined with chemotherapy is superior to other treatments in survival rate and survival time of primary gastric lymphoma.