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在寻找保肝生药的过程中,注意到枳椇子(Hovenia dulcis)具有对抗乙醇毒性的作用,枳椇子可加速人和大鼠体内乙醇代谢。本研究评价了枳椇子对脂多糖(LPS)诱发长期饲喂乙醇大鼠肝损害的保肝作用。 材料与方法:①使用枳椇子500g,粉碎后用水或甲醇回流提取2次(1.5L×2),每次3h。提取物经过滤冻干得甲醇提取物
In the search for liver-protecting crude drugs, it was noted that Hovenia dulcis has an effect against ethanol toxicity, and tweezers can accelerate the metabolism of ethanol in humans and rats. This study evaluated the liver protection effects of Gardenia jasminoides LPS on liver injury induced by long-term ethanol administration in rats. Materials and Methods: 1 Using wolfberry seeds 500g, pulverized and extracted twice with water or methanol (1.5L×2) each time for 3h. Extracts were freeze-dried to obtain methanol extracts