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近年来,痛风的发病率逐年增高,为探讨本病的临床特点,以期提高确诊率,减少发作频率,现将我院近年收治的临床资料完整的42例原发性痛风作一临床分析.1 临床资料1.1 一般情况 42例均为男性.确诊时年龄31~74岁.平均53.7岁;职业:脑力劳动者32例,体力劳动者10例;病程7天~30年,平均5.72年.诊断根据1985年美国Holmes提出的标准(陈慎仁,陈俊辉.痛风的诊断和治疗策略.新医学,1994,25(8):437),具备其中的一条并排除了继发性痛风.1.2 临床表现 主要为急性痛风性关节炎,发生在第(?)趾关节17例,踝关节11例,手指关节及膝关节各8例,其他足趾关节7例,腕关节及足背各3例,小腿部2例,肘关节1例.其中多个关节同时受累12例,有痛风石8例.起病急剧,受累关节或局部表现为红、肿、热、痛,疼痛以夜间为甚,持续数天,甚至2~3周后局部皮肤脱皮发痒,皮色呈紫红色,全身症状多较轻微.伴畏寒、发热7例,体温最高达38.8℃.
In recent years, the incidence of gout increased year by year, in order to explore the clinical features of the disease, in order to improve the diagnosis rate and reduce the frequency of seizures, now our hospital in recent years, clinical data of 42 cases of complete primary gout for a clinical analysis.1 Clinical data 1.1 The general situation of 42 cases were men .Analyzed age ranged from 31 to 74 years old .An average of 53.7 years; Occupation: mental work in 32 cases, manual workers in 10 cases; duration of 7 days to 30 years, an average of 5.32 years.According to 1985 Holmes proposed standards (Chen Shenren, Chen Junhui gout diagnosis and treatment strategies. New Medicine, 1994,25 (8): 437), with one of the exclusion of secondary gout.2.2 The main clinical manifestations of acute Gouty arthritis occurred in 17 cases of the first (?) Toe joint, ankle joint in 11 cases, finger and knee joints in 8 cases, other toe joints in 7 cases, wrist and dorsal in 3 cases, calf 2 Cases, elbow in 1. Among them, a number of joints involved in 12 cases at the same time, there are 8 cases of tophi. Rapid onset, affected joints or local performance of redness, swelling, heat, pain, pain even more at night for several days, Even 2 to 3 weeks after the local skin peeling itchy, skin color was purple, systemic symptoms are more minor with chills, 7 cases of fever, body temperature up to 38.8 ℃.