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目的:比较来曲唑与克罗氯米芬应用于多囊卵巢综合征患者的促排卵效果。方法:将该院2008年2月～2009年1月收治的76例多囊卵巢综合征患者随机分为两组,对照组38例采用克罗氯米芬治疗,观察组38例采用来曲唑治疗,比较分析两组的促排卵效果。结果:观察组的治愈率为18.4%,明显高于对照组的2.6%,两组间差异有统计学意义(P<0.05);观察组HCG注射日子宫内膜厚度为(9.14±1.35)mm,对照组为(5.39±0.62)mm,两组间差异有统计学意义(P<0.05)。结论:来曲唑应用于多囊卵巢综合征患者,疗效肯定,有利于子宫内膜的发育情况,值得在临床推广应用。
Objective: To compare the ovulation promoting effect of letrozole and clomiphene citrate in patients with polycystic ovary syndrome. Methods: 76 patients with PCOS admitted from February 2008 to January 2009 in our hospital were randomly divided into two groups. In control group, 38 patients were treated with clomiphene citrate, 38 patients in observation group were treated with letrozole Treatment, comparative analysis of two groups of ovulation induction effect. Results: The cure rate of the observation group was 18.4%, which was significantly higher than that of the control group (2.6%), the difference was statistically significant (P <0.05). The endometrial thickness of the observation group on the HCG injection day was (9.14 ± 1.35) mm (5.39 ± 0.62) mm in the control group, with significant difference between the two groups (P <0.05). Conclusion: Letrozole is used in patients with polycystic ovary syndrome. The curative effect is definite, which is in favor of the development of endometrium, which is worthy of clinical application.