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本文报导外用新中成药—双柏散软膏剂中总蒽醌的含量测定。研究结果表明:采用醋酸镁甲醇液比色法测定总蒽醌的含量,并将两年前制备的软膏和现在制备的软膏进行对比,置于波长512nm处测定,结果显示两者中的总蒽醌含量近相似,制剂的稳定性良好,同时此法操作简单,重现性好,为制订软膏剂的质控标准提供一定的依据。
This article reports on the determination of the total hydrazine in the topical new proprietary Chinese medicine-Shuangbaisan ointment. The results of the study showed that the content of total hydrazine was determined by the colorimetric method of magnesium acetate and methanol, and the ointment prepared two years ago was compared with the ointment prepared at present and was measured at a wavelength of 512 nm. The results showed that the total enthalpy was between the two. The content of hydrazine is similar and the stability of the preparation is good. At the same time, this method is simple and has good reproducibility. It provides a basis for formulating quality control standards for ointment.