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马兜铃素(马兜铃酸Aristolochicacid)是从马兜铃属植物提制的一类黄色结晶,主要成份为马兜铃酸A,即3,4-次甲二氧基-8-甲氧基-10-硝基-1-羧酸菲。分子式C_(17)H_(11)O_7N西德Madaus厂产品“Tardolyt”主要含马兜铃酸A和B。从广西马兜铃(A-ristolochia kwangsiensis Chun etHow)等提得的马兜铃素,主要成份亦为马兜铃酸A,尚含少量马兜铃酸B、C等。我们对广西马兜铃素进行了升白细胞作用与毒性实验,现报告如下:
Aristolochic acid (Aristolochic acid) is a type of yellow crystal extracted from the Aristolochia plant. Its main component is aristolochic acid A, which is 3,4-methylenedioxy-8-methoxy. Base-10-nitro-1-carboxylic acid phenanthrene. The molecular formula C_(17)H_(11)O_7N West Madaus plant product “Tardolyt” mainly contains aristolochic acids A and B. The main component of aristolochic acid obtained from A-ristolochia kwangsiensis Chun et How et al. is also known as aristolochic acid A, and contains a small amount of aristolochic acid B, C, etc. We have performed leukocyte-enhanced and toxicity experiments on Guangxi aristolochine, and the report is as follows: