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当一个工作细致的临床医生发现晚期肾功能衰竭(肾衰)患者有舒张早期杂音时,会着手进行广泛的心脏病学方面检查,因为主动脉瓣闭锁不全的存在,可减少肾脏置换治疗成功的机会。肾衰时出现的舒张期杂音是Salvesen于1938年发现,随后其他几位学者也相继发现,最近Barrat等作了文献复习。9%的末期肾衰患者听到这种杂音,特别是同时存在贫血、高血压和液体超负荷时。大多数病人的这种杂音随着上列异常的纠正而消失。功能性主动脉瓣闭锁不全是高血压、贫血和液体超负荷的—种已明确的并发症。因此,预期在肾衰时会更多发生,而且上述三种情况常常同时出现。通过对肾衰患者有关水化状态而进行的心脏功能检查,更进一步支持功能性闭锁不全的想法,但形成此杂音的确切原因仍难以捉摸。主动脉造影检查时,主动脉瓣
When a well-researched clinician finds early diastolic murmur in patients with advanced renal failure (renal failure), a broad cardiology checkup is initiated because the presence of aortic atresia can reduce the risk of successful renal replacement therapy opportunity. Diastolic murmurs during renal failure were discovered by Salvesen in 1938, followed by several others, and recently reviewed by Barrat et al. Nine percent of patients with end-stage renal failure hear this murmur, especially when both anemia, high blood pressure, and fluid overload are present. The murmurs of most patients disappear with the above abnormalities. Functional aortic valve atresia is hypertension, anemia and fluid overload - a clear complication. Therefore, it is expected to occur more frequently in renal failure, and the above three cases often occur simultaneously. The heart function test on hydration status in patients with renal failure further supports the idea of functional atresia, but the exact cause of this murmur is still elusive. Aortic angiography, aortic valve