本文报道了天花粉注射剂能增强假孕兔子宫的自发收缩活动,降低子宫孕酮受体(以下简称P-R)含量,使孕酮和P-R的结合常数(K_A)值下降,但不影响子宫雌二醇受体(以下简称E-R)及其K_A值,对假孕兔血浆孕酮浓度也无明显改变,提示子宫孕酮受体可能参与子宫活动的调节。天花粉增强假孕兔子宫的自发收缩的机理可能与其降低子宫P-R及其K_A值有关。 This article reported that trichotomous injection can enhance the spontaneous contraction of pseudo-pregnant rabbits and reduce the utero progesterone receptor (PR) content, so that the value of the association constant (K_A) of progesterone and PR decreases, but does not affect uterine estradiol The receptors (hereinafter referred to as ER) and their K_A values ​​also have no significant changes in plasma progesterone concentrations in pseudopregnant rabbits, suggesting that uterine progesterone receptors may be involved in the regulation of uterine activity. The mechanism by which trichosanthin enhances the spontaneous contraction of pseudopregnant rabbits may be related to the decrease of uterine P-R and its K_A value.