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目的:探讨中药联合益赛普治疗老年类风湿关节炎的疗效。方法:选择2008年2月—2011年10月我院收治的老年类风湿关节炎患者90例,按随机数字表法分为观察组和对照组,每组45例。对照组在常规疗法基础上皮下注射益赛普,观察组联合中药治疗。比较两组疗效、临床指标、实验指标及不良反应。结果:观察组总有效率为91.11%(41/45),对照组为73.33%(33/45),差异有统计学意义(P<0.05);两组用药12周时临床指标和实验指标均有明显改善(P<0.05),且观察组明显优于对照组(P<0.05);观察组不良反应发生率为6.67%(3/45),对照组为22.22%(10/45),差异有统计学意义(P<0.05)。结论:中药联合益赛普治疗老年类风湿关节炎能显著提高疗效,改善临床指标和实验指标,减少不良反应,值得临床推广应用。
Objective: To investigate the curative effect of traditional Chinese medicine combined with Yixipu in the treatment of rheumatoid arthritis in the elderly. Methods: Ninety elderly patients with rheumatoid arthritis who were admitted to our hospital from February 2008 to October 2011 were randomly divided into observation group and control group according to random number table. Each group included 45 cases. The control group was injected subcutaneously with Yisipu on the basis of conventional therapy, and the observation group was treated with traditional Chinese medicine. The curative effect, clinical indexes, experimental indexes and adverse reactions of the two groups were compared. Results: The total effective rate was 91.11% (41/45) in the observation group and 73.33% (33/45) in the control group, the difference was statistically significant (P <0.05). The clinical indexes and experimental indexes (P <0.05), and the observation group was significantly better than the control group (P <0.05). The incidence of adverse reactions in the observation group was 6.67% (3/45) in the observation group and 22.22% (10/45) in the control group, There was statistical significance (P <0.05). Conclusion: Chinese medicine combined with Yisipu treatment of senile rheumatoid arthritis can significantly improve the efficacy, improve clinical indicators and experimental indicators, reduce adverse reactions, it is worthy of clinical application.