本文报导2例甲减患者有肌肉僵硬伴不同程度软弱,肌质增加,甲状腺素含量降低,即Hoffm-ann综会征,其血清CPK含量高于正常10倍以上。肌电图示重复的正相波。应用甲状腺素治疗后,肌肉不正常消失,实验室异常也恢复。 甲减体肌病非常多见,有人提出获得性肌病患者中有5％为继发于甲状腺素缺乏症。甲状腺肌病表现可自深腱反射延迟至较严重的伴不同程度的肌 This article reports 2 cases of hypothyroidism in patients with muscle stiffness with varying degrees of weakness, increased muscle, decreased thyroxine, Hoffm-ann congregation, the serum CPK content higher than normal 10 times. EMG shows repeated normal phase waves. After the application of thyroxine, the muscles disappeared abnormally and the laboratory abnormalities recovered. Hypothyroidism is very common, it was suggested that 5% of patients with acquired myopathy is secondary to thyroxine deficiency. Thyroid myopathy performance can be delayed from the deep tendon reflex to more severe with varying degrees of muscle