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2013年7月3日,美国食品和药品管理局(FDA)发布信息~([1]),抗高血压药奥美沙坦可引起口炎性腹泻样肠病。FDA已批准更改所有含奥美沙坦药物的说明书。奥美沙坦是一种血管紧张素Ⅱ受体拮抗剂(ARB),通过选择性阻断血管紧张素Ⅱ与血管平滑肌血管紧张素Ⅱ受体的结合而阻断血管紧张素Ⅱ的收缩血管作用,用于治疗高血压,可单独应用或与其他降压药联合应用。口炎性腹泻样肠
July 3, 2013, the United States Food and Drug Administration (FDA) release information ~ ([1]), antihypertensive drug olmesartan can cause stomatitis diarrhea-like enteropathy. FDA has approved a change of instructions for all olmesartan-containing drugs. Olmesartan, an angiotensin II receptor antagonist (ARB), blocks the angiotensin II-induced vasoconstriction by selectively blocking the binding of angiotensin II to vascular smooth muscle angiotensin II receptor, For the treatment of hypertension, can be used alone or in combination with other antihypertensive drugs. Mouth inflammatory diarrhea-like intestine