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目的分析与探讨胺碘酮治疗急性心肌梗死后室性心律失常的临床效果。方法 82例急性心肌梗死后室性心律失常患者,按照入院先后顺序分为研究组与参照组,各41例。研究组患者予以胺碘酮治疗,参照组患者予以利多卡因治疗。对比两组临床疗效。结果研究组中25例治疗显效,13例治疗有效,3例治疗无效,治疗总有效率为92.68%(38/41);参照组中9例治疗显效,20例治疗有效,12例治疗无效,治疗总有效率为70.73%(29/41);比较差异具有统计学意义(P<0.05)。研究组中4例出现不良反应,其中心动过缓2例,低血压1例,浅静脉炎1例,不良反应发生率为9.76%(4/41);参照组中14例出现不良反应,其中心动过缓3例,低血压2例,浅静脉炎5例,心力衰竭加重1例,转氨酶上升1例,恶心呕吐2例,不良反应发生率为34.15%(14/41);比较差异具有统计学意义(P<0.05)。结论胺碘酮治疗急性心肌梗死后室性心律失常患者,疗效确切,且安全性高,可广泛推广。
Objective To analyze and investigate the clinical effect of amiodarone in the treatment of ventricular arrhythmia after acute myocardial infarction. Methods A total of 82 patients with ventricular arrhythmia after acute myocardial infarction were divided into study group and reference group according to the order of admission, 41 cases in each group. Patients in the study group were treated with amiodarone, and patients in the reference group were treated with lidocaine. Compare two groups clinical curative effect. Results In the study group, 25 cases were cured, 13 cases were effective, 3 cases were ineffective, and the total effective rate was 92.68% (38/41). In the reference group, 9 cases were effective, 20 cases were effective, 12 cases were ineffective, The total effective rate was 70.73% (29/41). The difference was statistically significant (P <0.05). There were 4 adverse reactions in the study group, including 2 cases of bradycardia, 1 case of hypotension and 1 case of superficial phlebitis. The incidence of adverse reactions was 9.76% (4/41). In the reference group, 14 cases showed adverse reactions, of which, 3 cases of bradycardia, hypotension in 2 cases, 5 cases of superficial phlebitis, heart failure in 1 case, elevated aminotransferase in 1 case, nausea and vomiting in 2 cases, the incidence of adverse reactions was 34.15% (14/41); the difference was statistically significant Significance (P <0.05). Conclusion Amiodarone in patients with ventricular arrhythmia after acute myocardial infarction, curative effect is exact, and high safety, can be widely promoted.