Kaposi氏肉瘤(Kaposi’s sarcoma,下称KS)于1872年由Kaposi首次报道,迄今仍然是皮肤和肿瘤科存在的现实问题之一。此种多灶性损害疾患,可能与其好侵犯皮肤、淋巴结和内脏的恶变本质有关。尽管曾进行过大量的学术研究,但对KS的病因、发病机理及组织发生学等问题仍然不够清楚。KS的组织学特征为梭形细胞增生,形成毛糙有裂缝和沟状外观的血管肿瘤。肿瘤 Kaposi’s sarcoma (KS) was first reported by Kaposi in 1872 and remains one of the real problems of the skin and oncology to this day. Such multifocal lesions may be related to their aggressive nature of malignant transformation of the skin, lymph nodes and internal organs. Despite numerous academic studies, the etiology, pathogenesis, and histology of KS remain unclear. Histological features of KS are spindle cell hyperplasia that results in rough, cracked, and gully-like vascular tumors. Tumor