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目的 探讨磁共振成像 (MRI)对婴儿痉挛症病因诊断的临床应用价值。方法 应用以色列ELSINTGEREXMR仪 2 .0 T ,对 31例West综合征头颅MRI进行回顾性分析 ;观察其髓鞘形成的进程 ,测量脑室大小和脑外间隙的宽度 ,探讨West综合征的影像学特征。结果 31例患儿中症状性West综合征 2 5例 (80 6 % ) ,隐源性 3例(9 7% ) ,原发性 3例 (9 7% )。MRI表现主要有 4种 :侧脑室周围白质软化灶 (又分为伴脑白质髓鞘化延迟和不伴髓鞘化延迟 ) ;脑白质髓鞘化延迟 ;其它异常者如脑室扩大合并脑外间隙增宽、单纯脑外间隙增宽、单侧脑室扩大、脑组织软化灶 ;无异常发现者。 10例白质髓鞘化延迟者 ,9例有围产期异常史。结论 MRI检查有助于寻找West综合征的病因 ,指导治疗 ,评估预后
Objective To investigate the clinical value of magnetic resonance imaging (MRI) in the etiological diagnosis of infantile spasms. Methods The MRI findings of 31 West syndrome patients were retrospectively analyzed by ELSINTGEREXMR 2.0 T in Israel. The process of myelination was observed. The width of ventricular space and extracerebral space was measured to explore the imaging features of West syndrome. Results Twenty-five patients (80 6%) had symptomatic West syndrome, 3 cases (9 7%) had cryptogenicity, and 3 cases (9 7%) had primary symptomatic West syndrome. There are four major manifestations of MRI: white matter lesions around the lateral ventricle (also divided into delayed and non-myelinated leukoplakia with myelination delay); white matter myelinization delay; other abnormalities such as ventricular enlargement associated with extracerebral space Broaden, pure brain gap widened, unilateral ventricular enlargement, brain tissue softening; no abnormal findings. 10 cases of white matter myelination delay, 9 cases of abnormal perinatal history. Conclusion MRI examination can help find the cause of West syndrome, guide the treatment and evaluate the prognosis