This paper describes an investigation of a high-strength concrete frame reinforced with high-strength rebars that was tested in the structure engineering laboratory at Shenyang Jianzhu University. The frame specimen was pseudo- dynamically loaded to indicate three earthquake ground motions of different hazard levels, after which the test specimen was subjected to a pseudo-static loading. This paper focuses on the design, construction and experiment of the test frame and validation of the simulation models. Research shows that a high-strength concrete frame reinforced with high-strength rebars is more eff icient and economical than a traditional reinforced concrete frame structure. In addition to the economies achieved by effective use of materials, research shows that the frame can provide enough strength to exceed conventional reinforced concrete frames and provide acceptable ductility. The test study provides evidence to validate the performance of a high- strength concrete frame designed according to current seismic code provisions. Based on previous test research, a nonlinear FEM analysis is completed by using OpenSees software. The dynamic responses of the frame structure are numerically analyzed. The results of the numerical simulation show that the model can calculate the seismic responses of the frame by OpenSees. At the same time, the test provides additional opportunities to validate the performance of the simulation models. This paper describes an investigation of a high-strength concrete frame reinforced with high-strength rebars that was tested in the structure engineering laboratory at Shenyang Jianzhu University. The frame specimen was pseudo- dynamically loaded to three ground ground motions of different hazard levels, after which the test specimen was subjected to a pseudo-static loading. This paper focuses on the design, construction and experiment of the test frame and validation of the simulation models. Research shows that a high-strength concrete frame reinforced with high-strength rebars In addition to the economies achieved by effective use of of materials, research shows that that frame can provide enough strength to exceed conventional reinforced concrete frame structures and provide acceptable ductility. The test study provides evidence to validate the performance of a high- strength concrete frame des Based on previous test research, a nonlinear FEM analysis is completed by using OpenSees software. The dynamic responses of the frame structure are numerically analyzed. The results of the numerical simulation show that the model can calculate the seismic responses of the frame by OpenSees. At the same time, the test provides additional opportunities to validate the performance of the simulation models.