卵母细胞低温贮藏后的妊娠与分娩

来源 :世界核心医学期刊文摘(妇产科学分册) | 被引量 : 0次 | 上传用户:tonfy1028
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To determine the potential of oocyte cryopreservation techniques. Retrospectiv e data analysis. A tertiary infertility center. Sixty-eight patients (29 to 37 years of age) undergoing assisted reproduction procedures for infertility proble ms. Oocytes from women treated for infertility were cryopreserved with a slow co oling/rapid thawing protocol in which 1,2 propanediol and sucrose were used as c ryoprotectants. Eighty-six thawing cycles were performed. Rates of survival aft er thawing, fertilization after intracytoplasmic sperm injection, cleavage, impl antation, and pregnancy. We treated 68 patients through 86 thawing cycles.. Seve n hundred thirty-seven oocytes were thawed, and 59 transfer cycles were perform ed. The survival rate was 37%. The fertilization and cleavage rates were 45.4% and 86.3%, respectively. A total of 15 clinical pregnancies were achieved with pregnancy rates of 25.4%per transfer and 22%per patient. There were three misc arriages, resulting in an abortion rate of 20%. Seventeen of the 104 transferre d embryos implanted, corresponding to an implantation rate of 16.4%. Thirteen b abies were born, 8 females and 5 males. Statistically significant results were o btained for fertilization, cleavage, and pregnancy rates. Our results show oocyt e cryopreservation may represent an alternative to embryo storage in selected cases. Sixty-eight patients (29 to 37 years of age) undergoing assisted recovery reproduction procedures for infertility proble ms. Oocytes from women treated for infertility were cryopreserved with a Eighty-six thawing cycles were performed. Rates of survival aft er thawing, fertilization after intracytoplasmic sperm injection, cleavage, impl antation, and pregnancy. We treated 68 patients through 86 thawing cycles .. Seve n hundred thirty-seven oocytes were thawed, and 59 transfer cycles were performed ed. The survival rate was 37%. The fertilization and cleavage rates were 45.4% and 86.3%, respectively. A total of 15 clinical pregnancies were achieved with pregnancy rates of 25.4% per transfer and 22% per patient. There were three misc arriages, resulting in an abortion rate of 20%. Seventeen of the 104 transferre d embryos implanted, corresponding to an implantation rate of 16.4%. Thirteen b abies were born, 8 females and 5 males. Statistically significant results were o btained for fertilization, cleavage, and pregnancy rates. results show oocyt e cryopreservation may represent an alternative to embryo storage in selected cases.
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