论文部分内容阅读
患者女,44岁。左鼻翼红斑2年,缓慢扩大3个月。皮肤科情况:左鼻翼淡红色斑,大小0.8cm×0.8cm,表面无破溃,触之有轻度浸润感,边界清楚。皮损组织病理示:肿瘤在真皮全层呈团块状浸润,瘤细胞核大,嗜碱性,癌巢与周围组织间有裂隙,周边细胞呈栅栏状排列。免疫组化标记:瘤细胞P63(+),Ber-Ep4(+),CK7(-),EMA(-),CEA(-),CD10(-),S-100(-);Ki67阳性率约20%。诊断:基底细胞癌。行手术治疗,预后良好。
Female patient, 44 years old. Left nose erythema 2 years, slowly expanded 3 months. Dermatology: left nose reddish spot, the size of 0.8cm × 0.8cm, no ulceration on the surface, touch a slight sense of infiltration, clear boundaries. Histopathological examination showed that the tumors were aggregated in the whole dermis, the tumor nuclei were large, basophilic, and there was a gap between the cancer nests and the surrounding tissues. The surrounding cells were arranged in a palisade pattern. Immunohistochemical markers: The positive rates of Ki67 in P63 (+), Ber-Ep4 (+), CK7-, EMA-, CEA-, CD10-, 20%. Diagnosis: Basal cell carcinoma. Surgical treatment, the prognosis is good.