随着年龄的增长 ,大脑形态学变化显著 ,即使是健康人 ,中年以后也会发生年龄相关的脑萎缩和白质异常。横断面研究表明 ,脑血管危险因素与渐进性脑萎缩、异常白质高密度信号 (ＷＭＨＩ)的出现及临床无症状性卒中有关。作者通过检查中年期脑血管危险因素与老年期脑萎缩的差异、白 With age, brain morphology changes significantly, even in healthy people, age-related brain atrophy and white matter abnormalities also occur after middle age. Cross-sectional studies have shown that cerebrovascular risk factors are associated with progressive brain atrophy, the appearance of abnormal white matter high-density signal (WMHI), and clinically asymptomatic stroke. The authors examined the differences in cerebrovascular risk factors in midlife and senile atrophy, white