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甾体避孕药对脂类、脂蛋白和载体蛋白的影响是评价其长期安全性的重要指标之一。甾体避孕药的影响 ,因其生物活性和剂量而异。目前认为外源性雌激素可使ＴＧ .ＨＤＬ -Ｃ和ａｐｏＢ的水平上升〔1,2〕,而孕激素则因其雄激素及抗雌激素活性而往往可诱发ＨＤＬ -Ｃ、ａｐｏＡＩ的
The effect of steroid contraceptives on lipids, lipoproteins and carrier proteins is one of the important indicators to evaluate their long-term safety. The effects of steroid contraceptives vary depending on their biological activity and dosage. It is currently thought that exogenous estrogen can increase the levels of TG, HDL-C and apoB [1, 2], whereas progestins often induce HDL-C, apoAI due to their androgen and antiestrogen activity