趋化因子(chemokine)是目前已知最大的哺乳类动物细胞因子超家族[1]。自1992年国际免疫学会议首次命名至今,已发现至少50余种趋化因子及20余种趋化因子受体。大量研究表明,趋化因子通过与其受体相互作用,在肺部感染性疾病中起到重要作用[2]。本文将就趋化因子及其受体的特性,以 Chemokine is the largest known mammalian cytokine superfamily [1]. Since the first international immunological conference was named in 1992, at least 50 chemokines and more than 20 chemokine receptors have been found. Numerous studies show that chemokines play an important role in infectious lung diseases by interacting with their receptors [2]. This article will be on the characteristics of chemokines and their receptors