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利用离体大鼠皮肤为渗透屏障,研究了祛寒理气涂膜剂中葛缕酮在促吸剂氮酮作用下的透皮效果。用气相色谱法测定葛缕酮。氮酮的促吸作用在一定浓度范围内随着浓度增加而增加,2%的氮酮促吸效果最佳,稳态流量为1701.0μg·cm-2。
Using the skin barrier of isolated rat as the permeability barrier, the transdermal effects of gecosterone in the diosgenin film was studied. Determination of carotenone by gas chromatography. Azeotropin-promoting effect increased with increasing concentration within a certain concentration range, and 2% azone had the best effect of promoting aspiration. The steady-state flow rate was 1701.0 μg·cm-2.