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对因治疗无效的复发性月经过多而行子宫内膜切除的40例进行前瞻性研究。平均年龄42.3±7.5岁,既往平均刮宫2.5次,无效的内分泌治疗3次。所有患者术前行宫腔镜检和分段诊刮,以排除子宫肌瘤、粘膜下肌瘤、腺囊型和腺瘤型增生、宫深>10cm及恶性疾病。 将病例随机分组,对照组10例,无药物治疗,并在第一次月经后的卵泡期(月经周期第5～9天)行内膜切除。另30例用Oviol 28处理28天,第29天刮宫后再随机分3组:第1组用炔雌烯醇(10mg/d)4周;第2组用丹那唑(600mg/d)4周;第3组在第29天注射1支达必佳(Decapeptyl-Depot),4周后内膜切除。所有内膜切除均用滚压球技术,内膜作多点
40 cases of endometrial resection due to recurrent menorrhagia with ineffective treatment were prospectively studied. The average age was 42.3 ± 7.5 years old, the average curettage 2.5 times in the past, invalid endocrine therapy 3 times. All patients underwent hysteroscopy and segmental curettage before surgery to rule out uterine fibroids, submucosal fibroids, glandular cystadenomas and adenoma hyperplasia, with a depth of> 10 cm and malignant diseases. The cases were randomly divided into control group (10 cases) without drug treatment and endometrial resection in follicular phase (menstrual cycle from the 5th to 9th day) after the first menstruation. The other 30 cases were treated with Oviol 28 for 28 days. On the 29th day after curettage, they were randomly divided into 3 groups: group 1 received ethinylestradiol (10 mg / d) for 4 weeks; group 2 received ranazol (600 mg / d) for 4 weeks Group 3 was injected with Decapeptyl-Depot on the 29th day and endometrial ablation after 4 weeks. All endometrial resection using rolling ball technology, endometrial for more points