在毛细管电泳仪上对苯海因、对羟苯海因等外消旋体进行了拆分条件的研究。建立制备苯甘氨酸和对羟苯甘氨酸过程中的反应物、中间体和产物的毛细管电泳手性分析方法。使用磷酸氢二钠 柠檬酸、磷酸 三乙醇胺电泳缓冲液 ,磺酰化β 环糊精作为手性识别试剂 ,6种化合物均获得满意的分离度 In the capillary electrophoresis on diphenylhydantoin, p-hydroxyphenhydramine and other racemates were split conditions. To establish a chiral capillary electrophoresis method for the determination of reactants, intermediates and products during the preparation of phenylglycine and p-hydroxyphenylglycine. Disodium dihydrogen phosphate citrate, triethanolamine phosphate electrophoresis buffer, and sulfonylated β-cyclodextrin were used as chiral recognition reagents. All six compounds showed satisfactory resolution