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鼠Doppel蛋白(叠朊蛋白)是一种新发现的朊蛋白样糖蛋白(PrP-like protein),糖基化前的分子质量(Mr)约为15 000,在幼年动物的小脑与成年动物的睾丸和心脏有高水平的表达,其编码基因(Prnd)位于相应朊蛋白基因(Prnp)下游16?
The mouse Doppel protein (PrP-like protein) is a newly discovered PrP-like protein with a molecular mass (Mr) of about 15 000 before glycosylation. In the cerebellum of young animals and adult animals Testis and heart have high level of expression, the coding gene (Prnd) located in the corresponding prion protein (Prnp) 16?