肺动脉高压是一种以肺血管重构为主要病理改变的肺血管增生性改变 ,其病因尚未完全阐明 ,治疗上缺乏有效的手段。基因治疗有望成为肺动脉高压的有效治疗手段。本文就基因治疗肺动脉高压的研究进展进行概述。 Pulmonary hypertension is a pulmonary vascular remodeling as the main pathological changes of pulmonary vascular proliferative changes, the etiology has not been fully elucidated, the lack of effective means of treatment. Gene therapy is expected to become an effective treatment of pulmonary hypertension. This article summarizes the progress of gene therapy for pulmonary hypertension.