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198 6年Murry等首次在犬缺血 再灌注 (I R )模型发现反复短暂缺血发作可使心肌在随后持续性缺血中得到保护 ,从而提出了缺血预适应 (Isch emic ?preconditioning ,IPC)心脏保护的概念[1] ,为缺血心肌的保护及其机理探讨开辟了崭新的领域。随
For the first time, Murry et al found that repeated episodes of transient ischemic attack in canine ischemia-reperfusion (I R) models in 6 years provided myocardial protection during subsequent persistent ischemia and proposed Ischmicron preconditioning (IPC ) The concept of cardioprotection [1] opens up completely new fields for the study of the protection of ischemic myocardium and its mechanisms. With