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1918年3月4日,一处位于美国堪萨斯州的军营发生流感,接着中国、西班牙、英国都发生了流感。当时的症状只有头痛、高烧、肌肉酸痛和食欲不振而已。但到了1918年秋季则在全球大量爆发,至1920年春季,在全世界造成约10亿人感染,近4000万人死亡。其名字来源,因为当时西班牙有800万人感染了流感,甚至连西班牙国王也感染了此病,所以被称为西班牙型流行性感冒。西班牙型流行性感冒是人类历史上最致命的传染病,在1918～1919年曾经造成全世界约10亿人感染,2千5百万到4千万人死亡(当时世界人口约17亿人);其全球平均致死率约为2.5%
On March 4, 1918, a flu was reported at a military camp in Kansas, United States, followed by a flu in China, Spain and the United Kingdom. The symptoms were only headache, fever, muscle aches and loss of appetite. However, by the fall of 1918, there were a large number of outbreaks in the world. By the spring of 1920, about 1 billion people were infected and nearly 40 million people were killed in the world. Its name comes from the fact that at that time, 8 million people in Spain were infected with the flu and even the king of Spain was infected with the disease, so it was called Spanish-type influenza. Hispanic-type influenza was the most deadly infectious disease in human history. Between 1918 and 1919, about 1 billion people were infected, 25 to 40 million people died (the world’s population was estimated at 1.7 billion) ; Its global average lethality is about 2.5%