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运用白细胞介素-2(IL-2)依赖细胞短期培养3H-Tdr掺入法测定18例反复呼吸道感染儿童的IL-2活性,结果为以(X±SDcpm值)2135±1106,与正常对照(3183±888)比,差异有非常显著性意义(P<0.01)。提示 IL-2活性低下在患儿反复呼吸道感染的发生中起重要作用,并与其多种免疫功能异常有关。
IL-2 activity in 18 children with recurrent respiratory tract infection was measured by 3H-Tdr incorporation assay using interleukin-2 (IL-2) -dependent cell short-term culture. The results were expressed as (± SDcpm) 2135 ± 1106, (3183 ± 888), the difference was significant (P <0.01). These results suggest that low activity of IL-2 plays an important role in the occurrence of recurrent respiratory tract infections in children and is related to a variety of immune dysfunction.