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目的 :通过观察 2 5例川崎病患儿急性期、恢复期PPD皮试结果 ,从而了解川崎病急性期、恢复期细胞免疫功能状态 ,并进一步认识其发病机理。方法 :分别于川崎病患儿急性期、恢复期作PPD皮试 ,并于 48～ 72h观察皮试结果。结果 :急性期PPD皮试阴性的川崎病患儿 ,恢复期多转为阳性 ,经统计学分析川崎病患儿恢复期PPD皮试阳性率极显著高于急性期 (X2 =9 93,P <0 0 0 5 )。结论 :川崎病患儿急性期免疫功能平衡状态失衡 ,细胞免疫功能受抑制。
OBJECTIVE: To observe the acute and convalescent PPD skin test results in 25 cases of children with Kawasaki disease so as to understand the state of Kawasaki disease acute and convalescent cell immune function and to further understand its pathogenesis. Methods: Children with Kawasaki disease acute and convalescent PPD skin test, and 48 ~ 72h skin test results were observed. Results: The children with Kawasaki disease who were negative in PPD skin test in the acute phase turned more positive in recovery period. The positive rate of PPD skin test in recovery period of children with Kawasaki disease was significantly higher than that in acute phase (X2 = 9 93, P < 0 0 0 5). Conclusion: Children with Kawasaki disease have unbalanced immune function in the acute phase and cellular immune function is inhibited.