急性中毒性肝炎是指药物或毒物所造成的急性肝脏损害。其中以药物引起的中毒性肝损害更为常见,占急性肝炎的4.4％。由于大多数药物都在肝内代谢,随着化学工业的发展和新药品种的不断增加,毒物或药物引起的肝损害亦随之增多。Francesco Orland报道近卅年来,与急性肝炎有关的治疗用药达100多种。多年来我们收治病毒性肝炎,也收治了一些中毒性肝炎,这两种疾病在鉴别诊断上有时相当困难。因此研究药物引起的肝脏损害的临床 Acute toxic hepatitis refers to acute liver damage caused by drugs or poisons. Among them, drug-induced toxic liver damage is more common, accounting for 4.4% of acute hepatitis. As most drugs are metabolized in the liver, with the development of the chemical industry and the continuous increase of new drug species, the liver damage caused by poisons or drugs also increases. Francesco Orland reports over 100 treatments of acute hepatitis in the recent years. Over the years we received viral hepatitis, but also admitted some of the toxic hepatitis, the two diseases in the differential diagnosis is sometimes quite difficult. Therefore, the study of drug-induced liver damage in clinical