论文部分内容阅读
血小板活化后可引起肠系膜血管微血栓形成、释放和激活炎症介质,加重肠粘膜炎症反应并参与溃疡修复过程,因此,它与溃疡性结肠炎(UC)的关系引人重视.由于CD62P(P选择素)、CD63抗原是活化血小板最特异和灵敏的分子标志物,本文选择这两项指标观察UC病的血小板功能.1 对象和方法1.1 研究对象 经临床确诊的UC患者34例,其中轻型10例,中型4例,重型20例.活动期24例,符合中重型标准,缓解期10例,符合轻型标准.正常人对照组20例.
Platelet activation can cause mesenteric vascular microthrombus formation, release and activation of inflammatory mediators, increase intestinal inflammation and participate in ulcer repair process, therefore, its relationship with ulcerative colitis (UC) of the attention .As CD62P CD63 antigen is the most specific and sensitive molecular markers of activated platelets, this paper selects these two indicators to observe the UC platelet function.1 Subjects and methods 1.1 The study of clinically diagnosed 34 cases of UC patients, including 10 cases of light , 4 cases of medium and 20 cases of heavy type.The active period was 24 cases, in line with the medium and heavy standard, 10 cases of remission, in line with the light standard.Control group of 20 normal subjects.