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目的:观察比较氨茶碱与多索茶碱治疗慢性阻塞性肺炎的临床疗效。方法:将2012年1月至2015年12月本院确诊的58例慢性阻塞性肺炎患者按随机数字表法分为实验组29例和对照组29例。对照组采用氨茶碱进行治疗,实验组患者给予多索茶碱治疗。治疗12天后,对比两组患者的治疗效果及不良反应。结果:实验组患者的总有效率、PCO2值和PO2值的改变明显优于对照组,差异有统计学意义(P<0.05);实验组不良反应发生率低于对照组,差异有统计学意义(p<0.01)。结论:相对于氨茶碱,慢性阻塞性肺炎患者给予多索茶碱治疗的临床疗效高,不良反应发生率低,有较高的临床价值。
Objective: To observe and compare the clinical efficacy of aminophylline and doxofylline in the treatment of chronic obstructive pulmonary disease. Methods: 58 patients with chronic obstructive pulmonary disease diagnosed in our hospital from January 2012 to December 2015 were randomly divided into experimental group (n = 29) and control group (n = 29). The control group was treated with aminophylline, and the patients in the experimental group were treated with doxofylline. After 12 days of treatment, the treatment effect and adverse reactions of the two groups were compared. Results: The changes of total effective rate, PCO2 value and PO2 value in the experimental group were significantly better than those in the control group (P <0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group, with significant difference (p <0.01). Conclusion: Compared with aminophylline, patients with chronic obstructive pulmonary disease treated with doxofylline have high clinical efficacy, low incidence of adverse reactions, and high clinical value.