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目的探讨影响胃癌根治手术患者预后的相关因素。方法回顾性分析有完整临床资料和随访记录的351例胃癌患者的资料,对可能影响胃癌患者预后的6项临床病理参数(包括患者性别、年龄、肿瘤部位、TNM分期,病理分型,化疗方法等)进行单因素和多因素回归分析。结果单因素和Cox回归分析显示TNM分期、病理分型、化疗方法与患者的预后均具有相关性(P<0.01);肿瘤部位在单因素分析中是影响胃癌患者手术预后的相关因素(P<0.01),而应用Cox回归模型分析显示肿瘤部位并非影响预后的独立因素(P>0.05)。结论 TNM分期、病理分型及化疗方法可以作为评估胃癌患者预后的独立指标,从而指导胃癌的治疗。
Objective To explore the factors that influence the prognosis of patients with radical surgery of gastric cancer. Methods The clinical data of 351 patients with gastric cancer who had complete clinical data and follow-up records were retrospectively analyzed. Six clinical pathological parameters (including gender, age, tumor location, TNM stage, pathological type, chemotherapy method Etc.) for univariate and multivariate regression analysis. Results The univariate and Cox regression analysis showed that the TNM staging, pathological typing and chemotherapy were correlated with the prognosis of patients (P <0.01). The location of the tumor in univariate analysis was related to the prognosis of patients with gastric cancer (P < 0.01). However, Cox regression analysis showed that the tumor location was not an independent prognostic factor (P> 0.05). Conclusion TNM staging, pathological typing and chemotherapy can be used as independent indicators to evaluate the prognosis of patients with gastric cancer, which can guide the treatment of gastric cancer.