通过测定唾液中药物浓度对定时释放片衣层处方进行筛选。测定了5名健康志愿者口服3种处方制剂后的药时曲线,并据此选择了最佳处方。利用本法筛选处方准确性高、操作简便,具有实用性。 By determining the drug concentration in saliva, the prescription of time release tablets was screened. Five healthy volunteers were tested after oral administration of three prescription formulations of the drug curve, and thus select the best prescription. The use of this method to filter prescription accuracy, easy to operate, practical.