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为了探索妇科阳虚证的神经-内分泌系统的变化,我们参照邝安坤(上海内分泌研究所)方法制作雌性阳虚动物模型,并观察了有关指标及中药对它的影响。1 材料和方法 雌性SD大鼠41只,体重180～200g,分为4组:①对照组9只,每只肌注生理盐水1ml/d,连续 14 d.②阳虚模型组 9只,每只肌注醋酸考地松4 mg/d,共 14 d.以上2组d 15断头处死。③阳虚生理盐水组11只,每只肌注醋酸考地松4mg/d,共14 d;d15起生理盐水1ml灌胃,2/d,连续8d。④阳虚甲蓉片组12只,每只肌注醋酸考地松4mg/d,共14 4d;d 15起用甲蓉片混悬液1片/ml灌胃,2/d,共8 d。以上2组于停药2 d断头处死。所有
In order to explore the changes in the neuro-endocrine system of gynecological Yang deficiency syndrome, we created a female animal model of yang deficiency by referring to the method of An Ankun (Shanghai Endocrine Research Institute), and observed relevant indicators and the influence of Chinese medicine on it. 1 Materials and Methods 41 female SD rats weighing 180-200 g were divided into 4 groups: 1 control group, 9 animals, each intramuscular saline 1 ml/d, continuous 14 d.2 Yang deficiency model group 9 Only the intramuscular dose of acetic acid testosterone 4 mg/d for 14 d. 3 11 yang-deficient saline groups, each 4mg/d of intramuscular dexamethasone acetate for a total of 14 days; d15 1ml normal saline solution, 2d, continuous 8d. 4 Yangrong Jiarong Tablets group of 12, each intramuscular acetaminophen 4mg / d, a total of 14 4d; d 15 with a Rongrong Tablets 1 / ml gavage, 2 / d, a total of 8 d. The above two groups were killed after 2 days of drug withdrawal. all