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采用放免分析(RIA)法,测定了偏头痛发作期26例,间歇期23例患者及正常对照20例颈外静脉及肘静脉血中降钙素基因相关肽(CGRP)和P物质(SP)含量。观察了英明格对国人偏头痛的疗效,测定并对比了英明格治疗前、后颈外静脉(EJV)血中CGRP和SP含量,结果显示:(1)偏头痛发作期EJV血中CGRP和SP含量显著性升高,而在肘静脉血中不升高。(2)头痛缓解后,EJV血中CGRP和SP含量降至正常水平。(3)英明格对国人也是止痛迅速,安全度高的治疗偏头痛发作的药物。
Radioimmunoassay (RIA) was used to determine the levels of calcitonin gene related peptide (CGRP) and substance P (SP) in 26 cases of migraine attack, 23 cases of intermittent period and 20 cases of normal control in the jugular vein and elbow vein. content. The curative effect of Yingmingge on migraine was observed. The levels of CGRP and SP in blood of exine jugular vein (EJV) before and after Yingminge treatment were measured and compared. The results showed that: (1) CGRP and SP in EJV blood in migraine attack period Significantly increased content, but not in the elbow venous blood increased. (2) The headache relief, EJV blood CGRP and SP levels dropped to normal levels. (3) Ying Ming grid is also a quick and safe analgesic for migraine attacks.