体外受精时卵母细胞单精子显微注射对自发性胚胎缺失的影响

来源 :世界核心医学期刊文摘(妇产科学分册) | 被引量 : 0次 | 上传用户:xuguanghong
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To determine whether pregnancies after IVF, with and without intracytoplasmic sperm injection (ICSI), have different early spontaneous loss rates. Retrospecti ve analysis of IVF/ICSI dataset. The Center of Reproductive Medicine, Arcispedal e Santa Maria Nuova, Reggio Emilia, Italy. Women undergoing IVF with or without ICSI. First-trimester sonography at 67 weeks to count the number of embryos wit h positive heartbeat. The number of embryos lost was calculated from a second-t rimester sonogram. Embryonic loss rates related to the initial number of embryos , maternal age <35 or ≥35 years, and IVF procedure. In vitro fertilization and ICSI had similar embryonic loss rates (odds ratio [OR] 1.2, 95%confidence inter val [CI] 0.91.7, and OR 1.3, 95%CI 0.91.8 for women aged <35 years and ≥35 yea rs, respectively). Younger women had fewer losses after IVF (OR 0.7, 95%CI 0.5 -0.9). Multiples had lower loss rates compared with singleton pregnancies. In v itro fertilization and ICSI have similar spontaneous embryonic loss rates. Facto rs other than the initial number of embryos, maternal age, and IVF technique, su ch as embryo quality or uterine environment, might be involved in the outcome of multiple pregnancies in assisted reproductive technology procedures. Retrospecti ve analysis of IVF / ICSI dataset. The Center of Reproductive Medicine, Arcispedal e Santa Maria Nuova, Reggio Emilia, Italy. Women undergoing IVF with or without ICSI. First-trimester sonography at 67 weeks to count the number of embryos wit h positive heartbeat. The number of embryos lost was calculated from a second-t rimester sonogram. Embryonic loss rates related to the initial number of embryos, maternal age <35 or ≥35 years, and IVF procedure. In vitro fertilization and ICSI had similar embryonic loss rates (odds ratio [OR] 1.2, 95% confidence inter val [CI] 0.91.7, and OR 1.3, 95 % CI 0.91.8 for women aged <35 years and ≥35 yea rs, respectively). Younger women had fewer losses after IVF (OR 0.7, 95% CI 0.5 -0.9). Multiples had lower loss rates compared with singleton pregnancies. In v itro fertilization and ICSI have simil ar spontaneous embryonic loss rates. Facto rs other than the initial number of embryos, maternal age, and IVF technique, su ch as embryo quality or uterine environment, might be involved in the outcome of multiple pregnancies in assisted reproductive technology procedures.
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