Dear Editor,Neural progenitor cells (NPCs) have proven potential to facilitate mechanistic studies of neurological disorders in vitro,as well as the discovery of new medicines.In addition,NPCs have been proposed as promising cell sources for cell replacement therapy of neurological diseases (Liu et al.,2012b).For these areas of study,experimental animals are indispensable models.Among the possible animal species,pigs are advantageous compared to rodents because of their physiological and anatomical similarities to humans (Lind et al.,2007).Despite the shown advantages of porcine models in different fields,their applications are significantly restricted due to the limited access of porcine cells,including NPCs.To date,encouraging breakthroughs have been made in obtaining NPCs from a series of species by different methods,including primary cell isolation from tissues,differentiation from pluripotent stem cells,and direct reprogramming from other somatic cells (Vierbuchen et al.,2010;Giorgetti et al.,2012;Lujan et al.,2012;Thier et al.,2012;Zhang et al.,2013).