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镉是严重污染环境的污染物之一,但有关经口摄入的镉在体内的吸收、分布与排泄的资料却较少。试验用体重240～290g的雄性大鼠,单只饲养于代谢笼中。每只大鼠一次经口摄入~(115m)镉(Cd(NO_3)_2)50μCi。从摄入同位素30分钟开始直到28天,每隔一定时间依次用戊巴比妥钠(5 mg/100 g体重)麻醉,抽取心脏血进行分析。然后解剖取出睾丸、副睾、精囊、前列腺、肝、肾、脾,并取迴肠(近盲肠端)和十二指肠(近胃端)各长5 cm,称重后用30%氢氧化钾溶液于90℃消化10分钟。用固
Cadmium is one of the pollutants that pollute the environment seriously, but there is less information on the absorption, distribution and excretion of cadmium in the body by oral intake of cadmium. Male rats weighing 240-290 g were housed alone in metabolic cages. Each rat received ~ (115m) cadmium (Cd (NO_3) _2) 50μCi orally. From 30 minutes into the isotope until 28 days, at regular intervals with sodium pentobarbital (5 mg / 100 g body weight) were anesthetized, blood was drawn for analysis. The testis, epididymis, seminal vesicles, prostate, liver, kidney and spleen were removed and the 5 cm long intestine (proximal cecum) and duodenum (proximal gastric end) Potassium solution was digested at 90 ° C for 10 minutes. With solid