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目的:探讨脑神经元移行异常的CT表现,提高对脑神经元移行异常的认识。材料和方法:回顾分析18例脑神经元移行异常病人的临床和CT资料。15例做了平扫,3例平扫后做增强扫描。结果:无脑回畸形和/或巨脑回畸形4例,其主要CT表现为整个脑表面光滑或部分区域光滑、平坦,脑回、脑沟消失,脑皮层增厚,脑白质减少。脑裂畸形11例,CT表现为大脑内出现横贯的裂隙,其壁由异位灰质组成,裂隙壁可以是融合型(Ⅰ型)或者是分离型(Ⅱ型)。灰质异位3例,CT表现为室管膜下或半卵园中心结节状或团块影,密度与脑灰质相似。本病以儿童多见,平均年龄12.5岁。临床上常表现为顽固性癫痫。结论:脑神经元移行异常是一种先天性神经元迁移畸形,通过脑神经元移行异常的各种CT征象分析,对于临床正确诊断和合理治疗均有重要价值。
Objective: To explore the CT manifestations of abnormalities in brain neurons and to improve their understanding of the abnormalities of brain neurons. Materials and Methods: Clinical and CT data of 18 patients with abnormal neurons were retrospectively analyzed. Fifteen patients underwent plain scan and three underwent enhanced scan after plain scan. Results: No aneurysm and / or giant brain deformity in 4 cases, the main CT manifestations of the entire brain surface smooth or part of the area smooth, flat, the brain back, sulci disappear, cortex thickening, white matter reduction. There were 11 cases of schizencephaly. The CT showed a transversal fissure in the brain. The wall consisted of ectopic gray matter. The fissure wall could be fused (type Ⅰ) or isolated (type Ⅱ). Ectopic gray matter in 3 cases, CT showed subependymal or semi-oval center nodules or mass shadow, density and gray matter similar. The disease is more common in children, the average age of 12.5 years old. Clinical manifestations of intractable epilepsy. CONCLUSION: The abnormality of brain neurons migration is a congenital neuronal migration deformity. Through the analysis of various CT signs of abnormalities of brain neurons migration, it is of great value for the correct diagnosis and reasonable treatment in clinical practice.