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为探讨新生小鼠胸腺细胞移植对荷瘤小鼠免疫功能的影响，将新生Ｋｍ小鼠胸腺细胞移植于荷瘤Ｋｍ小鼠皮下及腹腔内，采用重量参数、组织学、组织化学及图像分析仪检测等方法进行观察。结果显示，移植组实体瘤重量轻于未移植胸腺细胞的对照组，其胸腺、脾和腋下淋巴结的重量均重于对照组。移植组淋巴结副皮质区明显增大，并可见大量管腔扩张的毛细血管后微静脉。移植组脾动脉周围淋巴鞘增厚，胸腺皮质增厚，两器官的嗜派若宁细胞增多。结果表明，新生小鼠胸腺细胞移植可增强荷瘤鼠的免疫功能，主要是细胞免疫，并能抑制荷瘤鼠肿瘤的生长
To study the effect of neonatal mouse thymocyte transplantation on the immune function of tumor-bearing mice, newborn Km mouse thymocytes were transplanted subcutaneously and intraperitoneally in Km mice bearing tumor. The weight parameters, histology, histochemistry and image analyzer Detection and other methods for observation. The results showed that the weight of the solid tumor in the transplantation group was lighter than that of the control group without thymocyte transplantation, and the weight of the thymus, spleen and axillary lymph nodes in the transplantation group was heavier than that in the control group. Transplantation group lymph node paracortex significantly increased, and visible a large number of lumen dilated capillary venules. Peripheral lymphatic sheath thickening of the splenic artery in the transplantation group, thymus thickened, the two organ organophosphate cells increased. The results show that the newborn mouse thymocyte transplantation can enhance the immune function of tumor-bearing mice, mainly cellular immunity, and can inhibit the growth of tumor-bearing mice