目的探讨胃肠道间质瘤(GIST)的临床表现特点和治疗方法。方法对37例胃肠道间质瘤患者的临床资料进行回顾性分析。结果 37例中有34例有明显的临床症状(91.9%),19例因消化道出血就诊,18例因发现腹部肿块或有腹痛、腹胀等不全性梗阻症状就诊,3例无明显临床症状,体检时发现。37例患者均行手术治疗,CD117阳性37例(100%)。结论早期较难诊断,通过病理组织学及免疫组化检查可明确本病的诊断,手术是主要的治疗方法。对于有脏器转移者应高度重视。 Objective To investigate the clinical features and treatment of gastrointestinal stromal tumors (GIST). Methods The clinical data of 37 patients with gastrointestinal stromal tumors were analyzed retrospectively. Results Of the 37 cases, 34 cases had obvious clinical symptoms (91.9%), 19 cases were treated by gastrointestinal bleeding, 18 cases were diagnosed as having abdominal mass or having abdominal pain and abdominal distension, 3 cases had no obvious clinical symptoms, Physical examination found. Thirty-seven patients underwent surgery, with 37 cases of CD117 positive (100%). Conclusion Early diagnosis is more difficult, histopathological and immunohistochemical examination can confirm the diagnosis of the disease, surgery is the main treatment. For those with organ metastasis should attach great importance.