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已有资料表明 ,肿瘤细胞能分泌大量基质金属蛋白酶 (matrixmetallopro teinase ,MMP) ,且具有高转移倾向的肿瘤细胞分泌的金属蛋白酶的含量亦高 ,对肿瘤的侵袭和转移起着极为重要的作用〔1〕。基质金属蛋白酶 9(MMP 9,E .C .)是金属蛋白酶类的
It has been shown that tumor cells can secrete a large amount of matrix metalloproteinases (MMPs), and the high metastatic tendency of tumor cells to secrete high levels of metalloproteinases also plays an important role in the invasion and metastasis of tumors. 1〕. Matrix metalloproteinase 9 (MMP 9, E.C.) is a metalloproteinase