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目的探讨皮质下动脉硬化性脑病的病因、发病机理、诊断和治疗、脑ＣＴ表现。方法回顾性分析３８例经临床及脑ＣＴ诊断为皮质下动脉硬化性脑病的患者，均作了脑ＣＴ检查。结果（１）均有６～４０年不等的高血压病史，部分伴有多年吸烟史或伴Ⅱ型糖尿病史者病情较重。（２）脑ＣＴ均表现有不同程度的白质疏松（ＬＡ）及深部白质上软化灶、侧脑室扩大；大多数同时伴有皮质的小梗死（８４％）。结论Ｂｉｎｓｗａｎｇｅｒ病的直接病因即是高血压。对有长期高血压和进展性痴呆，伴有多发性腔隙卒中者，结合脑ＣＴ改变可考虑本病诊断，及时给予治疗，可延缓病程。
Objective To investigate the etiology, pathogenesis, diagnosis and treatment of subcortical arteriosclerotic encephalopathy and brain CT findings. Methods A retrospective analysis of 38 cases of patients with subcortical arteriosclerotic encephalopathy diagnosed by clinical and brain CT were made brain CT examination. Results (1) All patients had a history of hypertension ranging from 6 to 40 years. Some had a history of many years of smoking or a history of type 2 diabetes. (2) Brain CT showed varying degrees of white matter loosening (LA) and deep white matter softening, lateral ventricle enlargement; most accompanied by small cortical infarcts (84%). Conclusion The direct cause of Binswanger’s disease is hypertension. Long-term hypertension and progressive dementia, associated with multiple lacunar stroke, combined with changes in brain CT may consider the diagnosis of this disease, timely treatment, can delay the course.