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应用2,3-二氨基萘荧光测定法对36例食管癌患者癌组织与癌旁组织及血清中硒的含量进行了测定。结果表明,癌组织中硒含量平均为1.325±0.81μg/g干重,癌旁组织为0.893±0.68μg/g干重,两者差异显著(P<0.05);血清中硒含量为0.6033±0.0520μmol/L,对照组20例献血员血清为0.8034±0.0650μmol/L,亦有显著性差异(P<0.05)。提示硒在抗肿瘤的过程中有一定作用。
The 2,3-diaminonaphthalene fluorescence assay was used to determine the selenium content in cancer tissues, adjacent tissues and serum of 36 patients with esophageal cancer. The results showed that the average selenium content in cancer tissue was 1.325±0.81 μg/g dry weight, and the adjacent tissue was 0.893±0.68 μg/g dry weight, with significant difference (P<0.05). The selenium content in the serum was 0.6033±0.0520 μmol/L. In the control group, the serum of 20 blood donors was 0.8034±0.0650 μmol/L, and there was also a significant difference (P<0.05). It is suggested that selenium has a certain role in the anti-tumor process.