地方性燃煤型氟中毒是由于氟污染地区居民使用高氟煤而污染环境介质和食物,从而引起以氟斑牙和氟骨症为主要特征的一种慢性全身性疾病~([1])。身体从外界摄入的氟主要通过肾脏排泄,占总排泄量的90%左右,因此尿氟水平的高低可以体现出人体内的氟负荷量,同时能够较好反映近期当地人群摄入氟的情况,并辅助诊断地方性氟中毒~([2-4])。贵州省织金县 Local coal-fired fluorosis is a chronic systemic disease characterized by fluorosis and skeletal fluorosis due to the use of high-fluorine coal by residents in areas contaminated with fluoride, which pollutes environmental media and foodstuffs [1] . Fluorine intake of the body from the outside world mainly through the kidneys excretion, accounting for about 90% of total excretion, so the level of urinary fluoride can reflect the body’s fluorine load, and can better reflect the recent local population fluoride intake , And assist in the diagnosis of endemic fluorosis ~ ([2-4]). Zhijin County, Guizhou Province