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目的:探讨老年性上消化道溃疡出血中潘妥拉唑的治疗效果。方法:对本院2004-2009年收治的77例老年人脑出血伴上消化道出血患者,随机分配予潘妥拉唑组和西咪替丁组分别治疗。结果:潘妥拉唑组患者中平均显效时间、平均止血时间分别为(8.5±7.06)h、(18.45±14.32)h;西咪替丁组的(20±13.42)h、(38.45±22.35)h,两组比较,差异性明显(P<0.01),停用潘妥拉唑后再出血1例,西咪替丁组再出血6例,两组比较,差异有统计学意义(P<0.05)。结论:潘妥拉唑在老年人脑出血伴上消化道出血治疗效果佳,同时也能减少该出血病例1周内的复发率。
Objective: To investigate the curative effect of pantoprazole in elderly patients with upper gastrointestinal ulcer bleeding. Methods: A total of 77 elderly patients with hemorrhage of the upper gastrointestinal tract who were admitted to our hospital from 2004 to 2009 were randomly assigned to the group of ptolazole and cimetidine. Results: The average effective time and the mean time to hemostasis in the group of ptozolam were (8.5 ± 7.06) h and (18.45 ± 14.32) h, respectively, (20 ± 13.42 and 38.45 ± 22.35) in the cimetidine group, h, the difference was significant between the two groups (P <0.01). One case of bleeding after stopping the use of pantoprazole and six cases of cimetidine rebleeding again, the difference was statistically significant (P <0.05 ). CONCLUSION: The effect of pantoprazole in the treatment of cerebral hemorrhage with upper gastrointestinal bleeding in the elderly is good, and it can also reduce the recurrence rate within one week of the bleeding.