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目的:探讨介入治疗局部晚期宫颈癌的临床疗效。方法:回顾性分析我院91例行介入治疗的局部晚期宫颈癌患者临床症状缓解情况、不同分期患者介入治疗近期疗效、后续治疗及不良反应发生情况。结果:介入治疗后患者症状改善率为100%;随着分期增加,患者介入治疗近期总有效率呈逐渐下降趋势,但各分期总有效率之间比较,差异无统计学意义(P>0.05);本组91例患者中22例行1次介入治疗,31例行2次介入治疗,26例行3次介入治疗,12例行4次介入治疗。介入治疗后73例患者成功实施根治术,18例术后病理检查发现存在淋巴结阳性、脉管癌栓及宫旁浸润的患者与未能实施根治术的患者行放射治疗;所有患者均发生不同程度发热、白细胞减少以及消化道反应等常见症状,经对症处理后均于1周内消失,未发生其他严重不良反应。结论:介入治疗局部晚期宫颈癌临床疗效显著,安全性高,能够有效提高手术根治成功率。
Objective: To investigate the clinical effect of interventional treatment of locally advanced cervical cancer. Methods: A retrospective analysis of 91 cases of our hospital interventional treatment of locally advanced cervical cancer patients with clinical symptoms, patients with different stages of interventional treatment of short-term efficacy, follow-up treatment and adverse reactions. Results: After the interventional treatment, the symptom improvement rate was 100%. With the increase of staging, the total effective rate of interventional treatment decreased gradually. However, there was no significant difference between the total effective rates (P> 0.05) ; 22 patients in this group of 22 patients underwent 1 interventional therapy, 31 patients underwent 2 interventional treatments, 26 patients underwent 3 interventional interventions and 12 patients underwent 4 interventional interventions. Radical treatment was performed in 73 patients after interventional therapy. Radiotherapy was performed in 18 patients with positive lymph nodes, vascular thrombus and uterine infiltration in the pathological examination after operation, and all patients were treated with different degrees of radiotherapy Fever, leukopenia and gastrointestinal reactions and other common symptoms, after symptomatic treatment were within 1 week disappeared, no other serious adverse reactions. Conclusion: The interventional treatment of locally advanced cervical cancer has significant clinical efficacy and high safety, which can effectively improve the success rate of radical operation.